Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9248d7aafd11b5b59c76d3ae3f425fda http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03b692453c261b5ea1bcf62b44bcb096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25a614a93a6791e7b25240f6220a2cfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-324 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2014-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a4a811d5569ab4924bccbe3e6d39bbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_919d40e5759f7540dd5a31db4ea821ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62fc2a4332375e0cbc13ed319b4c8468 |
publicationDate |
2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015088979-A1 |
titleOfInvention |
Methods for the detection and quantification of circulating endothelial cells |
abstract |
The disclosure provides methods for detecting circular endothelial cells (CECs) in a non- enriched blood sample. The present disclosure is based, in part, on the unexpected discovery that CECs can be detected in non-enriched blood samples. The present disclosure is further based, in part, on the discovery that CECs can be detected in non-enriched blood samples by combining the detection of one or more immunofluorescent markers in the nucleated cells of a non-enriched blood sample with an assessment of the morphology of the nucleated cells. The present disclosure is futher based, in part, on the discovery that CECs can be detected in non-enriched blood samples by comparing the immunofluorescent marker staining and morphological characteristics of CECs with the immunofluorescent marker staining and morphological characteristics of WBCs. The methods disclosed herein serve to classify human subject in myocardial infarction (MI) patients or healthy controls. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11084034-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11701657-B2 |
priorityDate |
2013-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |