http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015083995-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0eb612c0b9355d59ae2bc868455fee27 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 2014-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aef0daa6129cc20abb1772f010fa4cca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49485451138efa8d77a54fcd8021d19e |
| publicationDate | 2015-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015083995-A1 |
| titleOfInvention | Pharmaceutical composition for treating chronic myeloid leukemia, containing liriodendron tulipifera l. bark extract |
| abstract | The present invention relates to a pharmaceutical composition for treating chronic myeloid leukemia, containing a Liriodendron tulipifera L. bark extract as an active ingredient, and more specifically, to a pharmaceutical composition for treating chronic myeloid leukemia, containing a Liriodendron tulipifera L. bark extract, which causes cell death by a change in mitochondrial membrane potential (MMP) in leukemia cells, and the cleavage of poly(ADP-ribose) polymerase (PARP) and caspase-3 related to a cell death pathway, in order to selectively inhibit the T315I mutant enzyme generated by the mutation of the BCR-ABL fusion gene, which is a gene causing chronic myeloid leukemia. |
| priorityDate | 2013-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.