| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9cc0863fc17e63625be5f5e3c9d2b8a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-14 |
| filingDate |
2014-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31d4a6745854458a2904f83639cd6f10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1e362d19d27630a2c9c5e63799413c2 |
| publicationDate |
2015-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015074050-A1 |
| titleOfInvention |
Methods for screening patients for resistance to angioinhibition, treatment and prophylaxis thereof |
| abstract |
A method for screening a patient for angioinhibition resistance and treating said patient having a disease susceptible to treatment via an anti-angiogenic agent. The screening method includes an assay for identifying the presence of angioinhibition resistance in patients by collecting patient blood or serum and subjecting it to a Chick Chorioallantoic Membrane (CAM) angiogenesis assay configured for accepting a human tumor wherein the human tumor xenograft includes a vasculature system. The screening method and assay further includes steps that include using the CAM results for identifying the endogenous pro- angiogenic non-peptide hormone concentrations of the blood sample by calculating the vascular activity of the vasculature system of the human tumor xenograft in the presence of anti-angiogenic drugs and inducing in the patient, a state of subclinical hypothyroidism prior to commencing anti-angiogenic treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10201616-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961204-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021214137-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11006620-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11351137-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4166653-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077082-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10695436-B2 |
| priorityDate |
2013-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |