http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015069660-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ded504b18a27b7d519fdb42769fa0b2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01F1-00 |
| filingDate | 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6583274e8c07973b4d64fae9f1835ed3 |
| publicationDate | 2015-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015069660-A2 |
| titleOfInvention | Methods and compositions for increasing hepcidin expression using modified iron binding/releasing transferrin |
| abstract | Provided are methods for increasing hepcidin expression, treating a disorder associated with iron overload, decreasing non-transferrin bound iron (NTBI), reducing spleen size, ameliorating ineffective erythropoiesis, decreasing iron uptake by erythroid cells, and increasing transferrin receptor 1 (TfR1) expression in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a modified iron binding/releasing transferrin, wherein said modified iron binding/releasing transferrin comprises an N-lobe and a C-lobe, and wherein one of said lobes binds iron, and wherein one of said lobes has a decreased binding affinity for iron. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018192973-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020201305-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017068089-A2 |
| priorityDate | 2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1135.