abstract |
Disclosed is ringlike flavone shown by the formula (I), or an isoflavone compound, or nitric oxide, hydrate, solvate, or metabolite thereof, or pharmaceutically accepted salt or prodrug. A 2 is -O- when A is -C(O)-; A 2 is -C(O)- when A is -O-; Q is -O-、-S-、-C(R 4 R 5 )-、-C(R 4 R 5 )O-、-OC(R 4 R 5 )-、-C(R 4 R 5 )N(R 6 )-、-N(R 6 )C(R 4 R 5 )-、-N(R 6 )-、-C(R 4 R 5 )C(R 4 R 5 )-、-C(R 4 R 5 )-S- or -S-C(R 4 R 5 )-; W is -(NHC(O)) 1~2 -、-(C 1 -C 3 ) alkylene-(NHC(O)) 1~2 -, formula (II), formula (III),formula (IV), or formula (V); or R 1 is connected to W to form the imidazole ring. The ringlike flavone or isoflavone compound of the present invention has a desirable anti-hepatitis C virus effect. |