Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7341727d37cce6264abb6e7c3de11540 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16145 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
filingDate |
2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2de0826d1c94477e84070b86e7a9c96a |
publicationDate |
2015-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2015063085-A1 |
titleOfInvention |
Novel influenza virus vector for virotherapy |
abstract |
The present invention provides a recombinant influenza virus vector comprising an NS gene encoding a truncated NS1 protein of at least 73 and up to 122 amino acids of the N- terminus of the respective wild type NS 1 protein, wherein said vector replicates in IFN- sensitive tumor cells and does not replicate in normal, non-tumor cells, and expresses a heterologous immunostimulatory polypetide. The invention further provides a pharmaceutical composition containing said influenza virus vector, its use for the treatment of cancer patients and methods for producing said influenza virus vaccine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104830811-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106562999-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022112595-A1 |
priorityDate |
2013-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |