http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015057047-A1

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filingDate 2014-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d270af70f2a70661505e36163653e578
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publicationDate 2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2015057047-A1
titleOfInvention Process for obtaining a molecule serving as an antimicrobial peptide elicitor
abstract The invention relates to a method for the enzymatic synthesis of lithocholic acid oleate and for the efficient purification of same. The lithocholic acid oleate is a molecule that serves as an antimicrobial peptide elicitor and has an indirect immunomodulating antimicrobial activity by inducing the expression or overexpression of antimicrobial peptides and type II interferon (interferon-γ). Lithocholic acid oleate is a derivative of lithocholic acid esterified with oleic acid at the alpha 3-hydroxy position. It is a yellowish oily liquid at ambient temperature, having a molecular weight of 641 gr/mol and the chemical formula C 42 H 72 O 4 . This molecule can be used alone or combined with ascorbic acid and/or glucose, which this invention demonstrates are antimicrobial peptide elicitors, for the treatment of human chronic degenerative and infectious diseases.
priorityDate 2013-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0HJT9
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0HJU0
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID34152
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ04178
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00493
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41773
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6GBX8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ94819
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0HJI1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WHQ9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HKP6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID408016
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID820
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0HJI4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69045
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69046
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69047
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69048
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HIG5
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID84753
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21328
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12703
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12704
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12705
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO59952
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID36948
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID28457
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12708
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID666
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67971
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67973
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ4KTA7
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397310
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24465
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419474451
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16132394
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP55884
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67974
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19515
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24261
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19593
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8284735
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID326058256
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0C8A8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA5PJB2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ59049
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67968
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DV59
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41522
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21329
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID623
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67969
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF7XQS2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID450193
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP67970
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8DWM8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7CNQ9
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF8AJL1
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419489531
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA6UX50
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16198951
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID286836
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ27ID4
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1673
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68989
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA6URC7
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID405790
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP81025
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68990
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68991
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04667
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP81423
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68992
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID101128133
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8E2H3
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DV89
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100033976
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DV94
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3UT41
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID138125
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9SPU7
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453421822
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68988
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102004444
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID281229
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID15978
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http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID5693
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO13339
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Total number of triples: 457.