| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F4-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N31-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F4-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-06 |
| filingDate |
2014-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb8e230daff8421b072134701191f88f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cabfe87b6b441930479eff8c9f2abab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5a18e91b74a822a7aaebbbe6d352b37 |
| publicationDate |
2015-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015053716-A1 |
| titleOfInvention |
Direct synthesis of ph-responsive polymer particles and application in control release of hydrophobic therapeutic compounds |
| abstract |
The present disclosure relates to a process for making a branched copolymer comprising reacting polymer monomers with macro-azo polyethylene glycol (PEG) initiators and cross-linkers, in the presence of a chain transfer agent, wherein said process comprises the step of traditional radical polymerization. The process further comprises a step of dialysis to obtain polymer nanoparticles. The process further comprises the step of loading the polymer nanoparticles with a hydrophobic compound. The present disclosure also relates to the use of the polymer nanoparticles for the slow release of a hydrophobic compound in a neutral or alkaline environment or the fast release of a hydrophobic compound in an acidic environment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110483754-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106543323-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11534375-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106543323-B |
| priorityDate |
2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |