http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015051256-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86e3fdfb690314e605bc56655fdf219b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-5217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-507 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-02 |
| filingDate | 2014-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e65e5d5e89ff2efe18de1f9afc0ecb6 |
| publicationDate | 2015-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015051256-A1 |
| titleOfInvention | Voxel-resolution myocardial blood flow analysis |
| abstract | A myocardial blood flow analysis scan includes incorporating a pharmacological kinetic model with the standard factor analysis model where each time activity curve is assumed to be a linear combination of factor curves. Pharmacological kinetics based factor analysis of dynamic structures (K-FADS-II) model can be applied, whereby estimating factor curves in the myocardium can be physiologically meaningful is provided. Additional optional aspects include performing a discretization to transform continuous-time K-FADS-II model into a discrete-time K-FADS-II model and application of an iterative Improved Voxel-Resolution myocardial blood flow (IV-MBF) algorithm. Where the model is applied without assumption that a right ventricle tissue curve and a left ventricle tissue curve obey a particular mathematical relationship, a least squares objective function can be applied to obtain estimates for parameters of the pharmacological kinetic model by applying a majorize-minimize optimization technique to iteratively estimate the curves. |
| priorityDate | 2013-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.