| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-82 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c8d1d8724eb05a8aa31e4ab81fea7c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49a9b19b39dd828f64ae3727c2b2371 |
| publicationDate |
2015-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015042249-A1 |
| titleOfInvention |
Methods of bh3 profiling |
| abstract |
In various aspects the invention provides methods of predicting sensitivity of a cancer cell to a therapeutic agent by contacting a test cell population BH3 domain peptide; measuring the amount of BH3 domain peptide induced mitochondrial outer membrane permeabilization in the test cell population; and comparing the amount of BH3 domain peptide induced mitochondrial outer membrane permeabilization in the test cell population to a control cell population that has not been contacted with the therapeutic agent. An increase in mitochondrial membrane permeabilization in the test cell population compared to the control cell population indicates the cell is sensitive to the therapeutic agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497756-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018514210-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9758539-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10568887-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016253957-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10739333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10562925-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10835537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624880-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11225511-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016253957-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11215608-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279694-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10267787-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10357488-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10259835-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9901574-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9540674-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3288964-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10422788-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10393733-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034710-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10682356-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10761086-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10132797-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793915-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530231-B2 |
| priorityDate |
2013-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |