| abstract |
The present invention provides a cyclic derivative compound having remarkable whitening effects and a chemical structure of general formula (I), or a pharmaceutically acceptable salt thereof. In the formula: A is derived from an aromatic cyclic compound; B is hydrogen, oxo (=O), amino (-NH 2 ), imino (=NH), a C 1 -C 10 saturated or unsaturated linear or branched alkyl group, an alkoxy group, a monoalkylamino group, or a dialkylamino group; C n , C n+1 and C n+2 are three adjacent carbons present in the cyclic compound; and n is a positive integer. R 1 is hydrogen, hydroxyl, a saturated or unsaturated linear or branched alkyl group or an alkoxy group, X and Y are selected from hydrogen, hydroxyl, a saturated or unsaturated linear or branched alkoxy group or an acyloxy group, and one of X and Y is hydrogen. Each of R 2 , R 3 , R 4 and R 5 is at least one substituent independently selected from hydrogen, alkyl, alkoxy, acyloxy, acyloxymethyl, oxo, hydroxyl, vinyl, nitrile, carboxaldehyde, carbonitrile and aldehyde. |