abstract |
A compound having Formula (I): wherein: R1 is selected from hydrogen, halogen, hydroxyl and C 1-4 alkoxy; R2 is selected from hydrogen, halogen, hydroxyl and C 1-4 alkoxy; R3 is C 1-4 alkyl; R4 is aryl which is substituted with a group selected from OSO 2 NH 2 , NHCONH 2 , NHSO 2 NH 2 , NHSO 2 C 1-4 alkyl and CONH 2 ; and n is 0 or 1; or a pharmaceutically acceptable salt thereof; provided that the compound is not N -(1-benzylpiperidin-4-yl)- N -methyl-4-(4-(sulfamoylamino)phenyl)-1 H -imidazole-1-carboxamide or N -(1-benzylpiperidin-4-yl)- N -methyl-4-(3-(methylsulfonamido)phenyl)-1 H -imidazole-1-carboxamide. The compound may be used as an inhibitor of fatty acid amide hydrolase. |