| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5f7ecf389caf63aba5e62eaa2a2c7b1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2301 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 |
| filingDate |
2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7c16fdebd14a074e62ef838042975b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca8703e088d04370c49a6aa0ba577cd8 |
| publicationDate |
2015-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2015014949-A2 |
| titleOfInvention |
Stimulation reagent, cutaneous substitute, cutaneous explant and method for reproducing the physiopathology of atopic dermatitis |
| abstract |
The present invention relates to the use of a pro-inflammatory stimulating reagent containing between 10 and 500 ng/mL of interleukin IL-1β to reproduce the physiopathology of atopic dermatitis in vitro and/or to alter the barrier function in a cutaneous substitute or a cutaneous explant. It also relates to a pro-inflammatory stimulating reagent containing: a. Between 10 and 500 ng/mL interleukin IL-1β, and b. Between 3 and 20 µg/mL of a ligand of the TLR-2 receptor, and/or c. Between 3 and 20 µg/mL of a ligand of the TLR-3 receptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11088430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023166269-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015101677-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3133198-A1 |
| priorityDate |
2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |