abstract |
The present invention belongs to the field of pharmaceuticals and chemicals, and relates to thiazole inner salt compounds, and a preparation method and use thereof. In particular, the present invention relates to compounds as shown by formula I, and hydrates or pharmaceutically acceptable salts thereof. The compounds of formula I of the present invention are potent crosslinking protein cleavage agent, and have a stable structure, good physical and chemical properties, and good pharmacological action; large-scale production can obtain samples with stable, controllable and reliable quality, and are suitable for developing into a drug. |