http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015001521-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_904ec80c3a8ad4a1a00b4e787bd180de http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fd9074e7f5629511f3a410b1316b5f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-395 |
| filingDate | 2014-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f5bf553e680ed90811635d6f2af6d27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_137d3fdd80a55a60f14d24cd41e75bd7 |
| publicationDate | 2015-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2015001521-A1 |
| titleOfInvention | Method for inducing targeted meiotic recombination |
| abstract | The invention concerns a method for inducing targeted meiotic recombination in a eukaryotic host cell, by co-expression in said cell of a first chimeric protein ME comprising an effector domain DE capable of inducing the formation of double-strand breaks in the DNA during meiotic recombination and an interaction domain DI1 formed by the first partner of a protein-protein pair having selective affinity, and a second chimeric protein comprising an interaction domain DI2 formed by the second partner of said protein-protein pair having selective affinity and a targeting domain DC capable of binding selectively with a target sequence present in the DNA of said host cell. The protein-protein interaction between domains DI1 and DI2 allow a non-covalent complex to form between module ME and module MC, and double-strand breaks to be induced by effector domain DE near the sequence targeted by targeting domain DC. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3081473-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019224324-A1 |
| priorityDate | 2013-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.