http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014210031-A9
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc408585f6863d7865c90ab9a4632135 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2014-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93b82a56fd3338778fc4daaa0c07864f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0733b0224c5d705874d9fb1b4bde6999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ba6f44634a17545d196f4c16b905f55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcf23ab1f186d32d873c48d0c4482fbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_158ac434370630a4d57edcba72b51beb |
publicationDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2014210031-A9 |
titleOfInvention | Proteomic biomarkers of sepsis in elderly patients |
abstract | A proteomic expression platform to identify age-related sepsis risk is disclosed using patients with community-acquired pneumonia. A semi-quantitative plasma proteomics workflow was applied which incorporated tandem immuno affinity depletion, iTRAQ labeling, strong cation exchange fractionation, and nanoflow-liquid chromatography coupled to high resolution mass spectrometry. A protein profile was determined that exhibit statistically significant differences in expression levels amongst patients with severe sepsis as a function of age. Representative pathways that are differentially-expressed include, but are not limited to, acute phase response, coagulation signaling, atherosclerosis signaling, lipid metabolism, and production of nitric oxide/reactive oxygen species. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109030834-A |
priorityDate | 2013-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419559537 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID945 |
Total number of triples: 19.