http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014206210-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eac2f8eff077c4682236f6b66083d39a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
filingDate | 2014-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6016270f7769889b7bf38f8fd5b5da6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a889ff0bd4656dedfe159cb2f2019407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51452f1ae2d12c5ccb57a40ac1984ac3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60ad196fe206e251fa71b4dee5944f73 |
publicationDate | 2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2014206210-A1 |
titleOfInvention | Method for preparing eptifibatide |
abstract | Provided is a method for preparing eptifibatide, wherein the method comprises: obtaining an eptifibatide refined peptide solution; and obtaining and freeze-drying an eptifibatide refined peptide concentrate after rotary evaporation of the eptifibatide refined peptide solution, wherein the concentration of the eptifibatide refined peptide concentrate is 15-30 mg/ml and the temperature of rotary evaporation is 251°C-35°C. The preparation method of the eptifibatide refined peptide solution is as follows: coupling Cys with a resin to obtain a Cys-resin; obtaining a polypeptide having a sequence as represented by SEQ ID NO: 1 by gradually coupling the Cys-resin with Pro, Trp, Asp, Gly, Har and Mpr; and obtaining the eptifibatide refined peptide solution through oxidation, cleavage, purification and transfer to salt. |
priorityDate | 2013-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.