| abstract |
Provided is an application method of a cyclodextrin multi-aldehyde cross-linking agent. In the cyclodextrin multi-aldehyde cross-linking agent, there are 2-3 acid groups per mole on average, which are used to modify collagen, the modification method comprising: mixing the aqueous solution of the cyclodextrin multi-aldehyde cross-linking agent and the collagen aqueous solution, freezing the obtained mixed solution in a mold to prepare modified collagen gel, taking out of the modified collagen gel after the mold is unfrozen at room temperature, and drying the modified collagen gel to obtain porous spongy modified collagen. |