http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014197775-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d6f7da1e425c8a3ef1da21e08f4c196 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D335-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f325f9dddf75dcff78077fa32672ae2 |
| publicationDate | 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2014197775-A1 |
| titleOfInvention | Thiourea compounds and their use as inhibitors of sirt2 or sirt5 |
| abstract | A compound useful as a Sirt2 or Sirt5 inhibitor having the formula (1) wherein: R 1 is a hydrocarbon group having at least two carbon atoms connected by carbon-carbon bonds, wherein said hydrocarbon group is optionally endcapped by a neutral or anionic oxygen-containing group; R 2a , R 2b , and R 2c are independently selected from hydrogen atom and hydrocarbon groups; X 0 , X 1 , X 2 , and X 3 are independently selected from -(CH 2 ) n -, -NR 5 -, -O-, -S-, and a bond, wherein n represents 1, 2, or 3, provided that at least one of X 0 -X 3 is -(CH 2 ) n -; and R 3 and R 4 are independently selected from the group consisting of hydrogen atom, hydrocarbon groups, biological groups, and protecting groups. Also described are pharmaceutical compositions of the inhibiting compounds, and methods of treatment by administration of the inhibiting compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020127958-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021113667-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114315670-A |
| priorityDate | 2013-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 623.