Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e02230e30f2fcaa0b4165ce78bf54f6e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0031 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
filingDate |
2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_385ed02411fa0802df9ef6274f121522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c2d611e50ce2df132f44f073cf2c4c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2588f49de4e41f2ac8de0a36be97d4f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de1f93c1ef00f8f029d17f7536296eee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bf2411fc41f6771552abe441f7c105d |
publicationDate |
2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014197754-A1 |
titleOfInvention |
Absolute quantitation of proteins and protein modifications by mass spectrometry with multiplexed internal standards |
abstract |
A method for absolute protein or peptide quantitation by mass spectroscopy. A sample containing a protein or peptide of interest is prepared for mass spectroscopy analysis. The sample is subjected to mass spectroscopy analysis at low resolution whereby a single additive mass spectroscopy peak is obtained, then is subjected to high resolution mass spectroscopy analysis whereby a plurality of mass spectroscopy peaks are obtained. The intensity of each of the plurality of mass spectroscopy peaks is quantitated either by comparison to an internal standard set, or by using a standard curve generated for each isotopologue set. Quantitation using a standard curve enhances quantitation across a dynamic range of analyte. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3092483-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017107639-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015106169-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020079614-A1 |
priorityDate |
2013-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |