http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014195965-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_200a357ba0b6fe61b7de5143cf8725b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea339162aeb73ca73bf4875107e5ad05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c32846a230f3176b48ba77b2c27e0de5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14517f9aa9e4b7ffbc0e1f065f5123bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_173384b68cf82f7aa7817ec197b5bb94 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5352 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-535 |
filingDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6b56f31622e1068ebaf620e217048a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03b8b4f661e934117ab6f850b07b568a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_464a4e4e4e1ae5a7d205a222c3edd8f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4b5be6475196f9b02dd7b6a9a1cd659 |
publicationDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2014195965-A3 |
titleOfInvention | An improved process for the preparation of hmg-coa reductase inhibitor intermediates |
abstract | The present invention relates to novel processes for the preparation of compounds of Formula-II useful as intermediates in preparation of HMG-CoA reductase inhibitors, and further conversion of said intermediates to HMG-CoA reductase inhibitors. The process for the preparation of compounds of Formula-II comprises reacting compounds of Formula-Ill with dimethylformamide dimethylacetal in the presence of a base to get compounds of Formula-IV, reacting the compounds of formula-IV with alkyl chloroformate in the presence of a base to get compounds of Formula-V, and converting the compounds of Formula-V into compounds of Formula-II. The compounds have the following structures, [Formulas should be inserted here] wherein X is hydrogen or hydroxy protecting group, R 1 is carboxyl protecting group, Alk represents C 1 -C 4 alkyl and R 2 , R 3 and R 4 are independently selected from substituted or unsubstituted C 6 -C 10 aryl groups. |
priorityDate | 2013-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.