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filingDate 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2014189654-A1
titleOfInvention Co-immunization with attenuated rabies virus and non-rabies antigen
abstract Provided is a method of enhancing an antigen-induced long-lasting immune response in a host comprising administering to a host an effective amount of: (a) a nonpathogenic recombinant rabies virus comprising at least three copies of a mutated G gene, wherein said mutated G gene encodes a rabies virus glycoprotein wherein the glycoprotein amino acid 194 is serine and the glycoprotein amino acid 333 is glutamic acid, wherein said recombinant rabies virus does not express a foreign protein antigen; and (b) a non-rabies antigen that is not expressed by the rabies virus. Also provided are related compositions, kits and vaccines.
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