Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82cbc291d77c061ac9a216f86ec010a3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2014-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2a2dd7cd660ae6ca1d6d5cfd445206d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_445dc0f6172803235abbcc7462a78971 |
publicationDate |
2014-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014188775-A1 |
titleOfInvention |
Method for preparing androgen receptor activity-dependent breast cancer cell line, screening method using cell line, and method, kit and marker for determining acquisition of androgen receptor activity dependence in breast cancer patient |
abstract |
The present invention addresses the problem of providing a cell line having a novel resistance mechanism that is completely different from the resistance mechanisms in conventional hormone therapy, a screening method using the cell line, and a method for determining whether or not a breast cancer patient has acquired the aforesaid resistance mechanism.nProvided are: a method for preparing androgen receptor activity-dependent breast cancer cells, said method comprising a step for culturing T47D-TE8 cells in an estrogen-depleted medium in the presence of androgen; a screening method using the breast cancer cells; and a method and a kit for determining the presence or absence of the acquisition of androgen receptor activity dependence in a breast cancer patient with the use of at least one member selected from the group consisting of KLK3, DDC and AR as an indicator. |
priorityDate |
2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |