| abstract |
Disclosed is a drug target capturing method, comprising the following steps: (1) preparing the raw materials: taking a compound, and DNA or RNA or one party of another exceptional affinity material; (2) bonding: covalently bonding the compound with the DNA or RNA or one party of another exceptional affinity material, to obtain a labeled compound; (3) delivery: with the gene delivery method, delivering the labeled compound obtained in step (2) to a cell; (4) target capturing: disrupting the cell in step (3), and capturing the DNA or RNA in step (1) with immobilized complementary DNA or RNA, or capturing the one party of the affinity material by using the other party of an immobilized exceptional affinity material, to enrich the target; (5) target identification; and (6) target determining. |