| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5605 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-481
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5601 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
| filingDate |
2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ecded2e067d1ab5f9551c2f64cb6742
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6997c02183490f2a0e51a6c7125afefe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c304c8db0cb4e33007ed74e6a79b061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d850fc8f0e9722c1ef6abf1c04a64d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d92adc33aceebb64f6886e349894d9bc |
| publicationDate |
2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014186737-A1 |
| titleOfInvention |
Compositions and methods for chemical exchange saturation transfer (cest) based magnetic resonance imaging (mri) |
| abstract |
Compositions and methods for chemical exchange saturation transfer (CEST) based magnetic resonance imaging (MRI) or frequency labeled exchange (FLEX) imaging are disclosed. Beta-hydroxycarboxylate and beta-aminocarboxylate derivatives including salicylic acid, salicylates, salicylic acid prodrugs, N- alkyl/aryl/acyl/sulfonyl-anthranilic acid analogs, and any aromatic compound with OH/NH group ortho to the carboxylic acid group are disclosed. Such compounds can be used as general MRI organic contrast agents and produce significantly improved contrast in MR images detectable through CEST or FLEX. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11573283-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2023016293-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10688198-B2 |
| priorityDate |
2013-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |