Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_854d0f7efc1e433ec4291a5320b57908 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C4-134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C8-0013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C19-063 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61C8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
filingDate |
2014-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6c5649056843d164772b62fa8cbc89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f68118d94215eb371873f6d0f5afd004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60fd731995c98a6c754e1f3297458424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8038e7b93225043148cb646020d1b2aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc742d608244b9710629ae7a2eb1d700 |
publicationDate |
2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014174437-A1 |
titleOfInvention |
Method for drug loading hydroxyapatite coated implant surfaces |
abstract |
A method for loading a hydroxyapatite coated implant with a therapeutic agent including the steps of providing an implant and applying a hydroxyapatite coating on a surface of the implant. The hydroxyapatite coated implant is contacted with a solution including the therapeutic agent. The hydroxyapatite coated implant and solution is heated to temperature of about 60 ˚C to about 100˚C. Pressure is applied to the hydroxyapatite coated implant and solution from about 2 bar to about 10 bar, to load the hydroxyapatite coated implant with the therapeutic agent. An implant made according to the method has sustained therapeutic agent delivery and includes a base and a biomimetic hydroxyapatite coating disposed on a surface thereof. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106756744-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112121227-A |
priorityDate |
2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |