| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62bf2c8e3be7f282db6e658eb393bed1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-38 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2014-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f2d2fcd787802d0c169f88b3184ddf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af4644f0484bc34a094ca73b5631b74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed534cb15f761fb3c452f9daed627ce9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95567b0fca673932e0718b0aa6a001ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b295d2c22c68429d8e3f4fee6795513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ff2ffb1aa6e6d25523f1192ffdeba22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57fc11f1514a638407381961c2bbcfa6 |
| publicationDate |
2014-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014154651-A1 |
| titleOfInvention |
Biological assay of peptidoglycans |
| abstract |
The present invention relates to a biological method for assaying peptidoglycans (PGN) in a sample, particularly a sample of glucose polymers. The PGN assay includes: a) treating the glucose polymer sample by sonication, heating, and/or alkalizing; b) placing the treated sample or a dilution thereof in contact with a recombinant cell expressing an exogenous TLR2 (toll-like receptor 2) and a reporter gene directly dependent on the signaling pathway associated with the TLR2. The reporter gene codes for a colored or fluorescent protein or for a protein the activity of which is measurable with or without a substrate; c) measuring the reporter gene signal; and d) determining the amount of PGN in the sample using a standard curve of the correlation between the amount of PGN and the strength of the reporter gene signal. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351895-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015118267-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3102692-B1 |
| priorityDate |
2013-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |