http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014152207-A1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
filingDate 2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0780d347a8d9cc4ca13df38b97e90c6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f390368903fa0e9b5304dad7fe25b5d8
publicationDate 2014-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2014152207-A1
titleOfInvention Hot melt granulation formulations of poorly water-soluble active agents
abstract The presently disclosed subject matter is directed to a granule, wherein the granule has an active agent and a wax dispersed therein, and the granule exhibits excellent friability when compressed to form a pharmaceutical composition. The subject matter disclosed herein is also directed to methods of preparing the granules and the pharmaceutical compositions comprising the granules. The compositions and methods disclosed provide granules and pharmaceutical compositions for immediate release of the active agent and do not substantially prolong the release of the active agent from the granule.
priorityDate 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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