Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C99-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B20-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16C20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16C20-64 |
filingDate |
2014-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d635600f07d90d02cf3e3f3b314131f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fecd14f4aabec851b7aff99770a4b97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09422f4a6ae42d32c1dbe6b4ebc13b3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f963c4d06d3857951c019acdbd7132aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_540183f52ea1dc9ba0e6f1f22473a5cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c327f2c6ff954afc82b16428a86b9a |
publicationDate |
2014-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014150173-A1 |
titleOfInvention |
Method for identifying inhibitors of protein-protein interaction |
abstract |
A method of using NMR and combinatorial synthesis to identify compounds that bind to a target protein is provided. Embodiments of the present disclosure are directed to methods of making compounds including one or more fragments that bind to a target protein. The target protein may be one which is known to have a binding partner. The compound including one or more fragments that bind to the target protein may be an inhibitor of the binding or other interaction between the target protein and binding partner. According to one aspect, binding fragments are attached to a polypeptide backbone in a conformation which allows binding of the fragments to the target protein. |
priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |