Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30e42c2252a6e67fcb19ee6411fe119b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2014-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec8795312221ac78f4d40315a8c346e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16651ccb98a74ed1d6d0fb87feb78444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf272b454c36d6790fb48452adf128f1 |
publicationDate |
2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014145836-A1 |
titleOfInvention |
Method of generating an index score for mbl deficiency to predict cardiodiabetes risk |
abstract |
This application relates to methods of predicting susceptibility or likelihood of a clinically-relevant mannose-binding lectin (MBL)-deficient subject to develop a cardiovascular disease and/or cardiodiabetes. The methods include measuring MBL mass or concentration and, optionally, measuring MBL activity, at least one other biomarker and/or or genotyping of MBL gene and its promoters; combining the information obtained into a calculated MBL- inclusive index score that involves mathematical transformation; and assigning a risk of cardiadiabetic status and clinical endpoints based on the determination and comparison of the MBL inclusive index to reference values from a population. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11699094-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020134363-A1 |
priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |