| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
| filingDate |
2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f43beada662c030afdda2ae8c0381886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1755df9948c6194aa083761af33e80fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32397814e3e073a935b73bba04785353 |
| publicationDate |
2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014144744-A1 |
| titleOfInvention |
Aptamer methods and compositions |
| abstract |
Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof. Among the various aspects of the present disclosure is the provision of methods and compositions for determining amino acids in dilute-and-measure assays directly from bodily fluids through aptameric sensor/derivatization, complexation, and host-guest complex formation. One aspect provides a method for isolating an aptamer. In some embodiments, the method includes providing a target molecule; providing a derivation agent; contacting the target molecule and the derivation agent to form a target complex; providing an oligonucleotide library comprising a plurality of aptamer candidates; contacting the target complex and the oligonucleotide library; and isolating an aptamer that binds to the target complex. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10620185-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107066838-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107066838-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10546650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114609210-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9863930-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11670400-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109541111-A |
| priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |