| abstract |
A method for predicting the severity or progression of OA in a human subject, comprising: determining the identity of at least one allele at each of at least 4 positions of single nucleotide polymorphism (SNPs) selected from the group consisting of: rs2206593, rsl0465850, rs780094, rsl374281, rsll43634, rs2073508, rs2243250, rs4720262, rs917760, rs7838918, rsl2009, rs730720, rs874692, rs893953, rsl799750, rsl0845493, rsll054704, rs7986347, rsl802536, rsl0519263, rs7342880, rsl6947882 and rsl0413815, and one or more SNPs in linkage disequilibrium at a level of at least R2 ≥0.8 therewith, as well as products, in particular systems and kits for use in such a method. |