abstract |
An esterified cellulose ether which comprises (i) aliphatic monovalent acyl groups or (ii) groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, and which has a) a viscosity of from 1.2 to 1.8 mPaos, measured as a 2.0 wt% solution of the esterified cellulose ether in 0.43 wt% aqueous NaOH at 20 °C, or b) a viscosity of up to 5 mPa•s, measured as a 10 wt% solution of the esterified cellulose ether in acetone at 20 °C, or c) a combination of the viscosities of a) and b), is useful for preparing solid dispersions comprising drugs. |