Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5cd84f92e5e2ff95dfd19e4e329db3b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
filingDate |
2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb78db69a941a21f87ff8c2412068705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea38dae27679193d76db616c8b0c98be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_333dd8c7dd4e9cfe5b281e72b31e35f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c50acfc8ac3215893789002960423a77 |
publicationDate |
2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014134071-A1 |
titleOfInvention |
Formulations and methods for increased recombinant protein production |
abstract |
Formulations and methods to increase the production of recombinant proteins, and other aspects, are disclosed. The formulations and methods relate to increasing mannose or calcium concentration, or both, in a cell culture medium formulation for culturing cells that express recombinant proteins. In some embodiments, a mammalian cell culture medium formulation is provided that has at least one of mannose at about 3.5 g/L or more and calcium in a range from about 1.5 mM to about 9.5 mM. Numerous other aspects and/or embodiments are provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3409783-A1 |
priorityDate |
2013-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |