| abstract |
Devices and methods for performing FISH (Fluorescent/Fluorescence In Situ Hybridization) analysis of biological and/or chemical samples are described, such as, on a substrate or slide. Some of these relate to FFPE (Formalin-Fixed, Paraffin-Embedded tissue and circulating tumor cell sample(s) FISH probe addition and hybridization. Automated systems and methods for performing analysis of FFPE tissue and circulating tumor cell sample(s) utilizing FISH probe addition and hybridization are advantageously incorporated. Some desirable advantages and benefits include novel and inventive methods and technologies for precisely identifying, locating and isolating regions or areas of interest for FISH by providing a barrier to isolate said regions or areas such that expensive probe, and other reagents, can be utilized in an efficient and economical manner, to maximize or enhance process efficiency. |