| abstract |
The present invention provides novel substituted imidazo[4,5-c]quinoline derivatives of formula (1), which may be therapeutically useful, more particularly as Bromodomain inhibitors; (1) in which Cy i , Cy 2 , R 1 , R 2 , R 3 , R 4 and R 5 have the same meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder associated as bromodomain inhibitors. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the substituted imidazo[4,5-C]quinoline compounds of formula (1) together with a pharmaceutically acceptable carrier, diluent or excipient therefor. |