| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d36a5393ba2d34a292205901b92681e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_901e6740f063c71e0a2b3f13f246cde8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_807e44790a710102e158f17f1b8a8e11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a349f8f884eafed4d885cf75c7e0382f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3110670ae97dbadd8800fa3d5b82687c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4092ece3ecb7973c495978b83898002f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2014-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfda9d8202452527084107d34c732590
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f8e4d03a5f4d90ab65d3db9f5c19d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93de6e3925715653e2a80838995c3d29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e616bcb29372aa7590531d652910893f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d605359741f2c661f6f08459089ae703 |
| publicationDate |
2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014126828-A9 |
| titleOfInvention |
Novel ph-switchable peptides for membrane insertion and pore formation |
| abstract |
Disclosed herein is a pH-switchable pore formation (PSPF) peptide comprising one or more amino acids in peptide sequence whose charge state and hydrophobicity are pH-dependent, wherein the peptide can bind to a biological membrane upon contact and form pores on the membrane at pH of less than about 7, and wherein the peptide forms substantially no pores on the biological membrane at pH of greater than about 7. Also disclosed is a modular composition comprising: a) one or more PSPF peptides, which may be the same or different; b) a single stranded or double stranded oligonucleotide; and c) one or more linkers, which may be the same or different. |
| priorityDate |
2013-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |