| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-327 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3015 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 |
| filingDate |
2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569c2bb841af75ae224fdc9363dddea3 |
| publicationDate |
2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014123484-A1 |
| titleOfInvention |
Methods For Reducing Aggregate Content In Protein Preparations |
| abstract |
A method of reducing aggregate and product-contaminant complex content in a protein preparation including a desired protein includes (i) contacting the protein preparation with at least one solid surface comprising at least one surface-bound ligand capable of binding a metal, the surface-bound ligand being capable of binding a metal is initially substantially devoid of a metal, the operating conditions are selected to substantially prevent the binding of the desired protein to the at least one solid surface and (ii) separating the protein preparation from the surface-bound ligand, such that when more than one surface- bound ligand is present, each surface-bound ligand is independently either of the same net charge or charge neutral. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017217930-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9376464-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793593-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927145-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9410181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3995196-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9803165-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160784-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022096499-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233211-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3110829-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9731288-B2 |
| priorityDate |
2013-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |