| abstract |
A VEGF-Ax polypeptide, as well as a smaller Ax polypeptide, both having anti-angiogenic activity that can be used for treating or preventing angiogenesis are described. An antibody specific to the Ax region of a VEGF-Ax polypeptide, as well as an antibody specific to the C-terminus region of a VEGF-A polypeptide that is not capable of binding to VEGF-Ax, and methods of using these antibodies, are also described. |