abstract |
The present invention relates to a method for preparing a protein combination-based Fv library, a method for screening a target antibody by using the prepared Fv library, an Fv antibody screened by the screening method, and an Fv library prepared by the method for preparing an Fv library. The Fv library of the present invention is based on a protein combination, thereby enabling individual function examination, and allowing a desired Fv antibody to be screened without a target antigen, and the frequency of protein purification remarkably decreases compared with a conventional DNA-based library, thereby reducing costs and time. |