abstract |
The invention relates to an industrial scale process for the preparation of 1-cyclopropyl-2-(2-fluorophenyl)ethanone of Formula (1) (Formula (1)) and the use of this compound for the preparation of 2-acetoxy-5-(2- fluoro-α-cyclopropylcarbonylbenzyl)-4,5,6,7-tetrahydro-4H-thieno[3,2-c]pyridine (prasugrel) of Formula (5). ((Formula (5)) |