Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01289 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64 |
filingDate |
2013-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_818420efd7b5ccd9f7336fc0fcb45513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cecea01f73ce0270eb7ca983449e9c8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007e96a3b4a30231e6482bc4ee0aaa43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc4be666277b305a081f416a1201775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c46fdd8d8fa0d1dbab01fae03c783b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5346631152dadce7211fd01ce3228546 |
publicationDate |
2014-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014100061-A1 |
titleOfInvention |
Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
abstract |
Recombinant microbial cells are disclosed herein that comprise (i) a down-regulation of an endogenous polynucleotide sequence encoding Sou2 sorbitol utilization protein, and (ii) a polyunsaturated fatty acid (PUFA) biosynthetic pathway. The down-regulation of the polynucleotide sequence encoding Sou2 sorbitol utilization protein can increase the lipid content of the microbial cells and/or decrease the total amount of sugar alcohols produced by the microbial cells. Also disclosed are methods of using the recombinant microbial cells to produce oil containing omega-3 polyunsaturated fatty acids such as EPA. |
priorityDate |
2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |