abstract |
The invention concerns BET-protein-inhibiting, in particular BRD4-inhibiting, dihydroquinoxalinones of general formula (I), in which A, X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and n have the meanings given in the description, intermediates for producing the compounds according to the invention, pharmaceutical agents containing the compounds according to the invention, and their prophylactic and therapeutic use in hyperproliferative diseases, in particular tumour diseases. The invention further concerns the use of BET-protein-inhibitors in viral infections, neurodegenerative diseases, inflammatory illnesses, atherosclerotic diseases, and male fertility control. |