| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 |
| filingDate |
2013-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa6ddfe0882888cdbccb6a23945544ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b6f513c2e6966ee3aa4540367582bb9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06146c725371432ddbe8c1796dacbaba |
| publicationDate |
2014-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014090715-A1 |
| titleOfInvention |
Thiazole derivatives as inhibitors of bruton's tyrosine kinase |
| abstract |
This application discloses compounds according to generic Formula I: wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11505547-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019106156-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019106146-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3492454-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11655246-B2 |
| priorityDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |