| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d4be1122ac19a1f6b4b45a73b1645f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2013-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37b9f616b9b0a9c9af7638d469378b0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fd8c3df04f6dd7a3af5f30df049e370
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a761612be680ebeaa7f5b835ad9131 |
| publicationDate |
2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014078898-A1 |
| titleOfInvention |
Chemotherapy for drug-resistant cancer cells |
| abstract |
The present invention relates to new treatments of multidrug resistant disorders, particularly cancers. There is provided a method of treating a cancer including administering an effective amount of a semicarbazone or hydrazone compound to a patient that has cancer, the cancer including a cancerous cell that includes an active efflux mechanism; wherein the compound is a substrate of the active efflux mechanism and the compound is able to form a chelation complex with a metal species in the cancerous cell, the chelation complex being cytotoxic to the cancerous cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017058748-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017175018-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109265453-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105396142-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104844632-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105396142-A |
| priorityDate |
2012-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |