abstract |
A problem to be resolved by the present invention is to allow filamentous fungi to be cultured in high density, and a useful substance to be thereby mass-produced. The present invention provides a method for manufacturing a substance, the method including: a step for culturing mutant-type filamentous fungi that do not express α-1,3-glucan, and causing the filamentous fungi to produce the substance; and a step for collecting the substance that was obtained. |