| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be944a7839fc8cabe752928d03dafaa4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0639 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99af246d93831b9d2b3ae8dbc3ac1fc9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2da4d202e9077bcdc4f415b7babc82a3 |
| publicationDate |
2014-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014072441-A1 |
| titleOfInvention |
Modulation of monocytes, or precursors thereof, differentiation |
| abstract |
The invention is generally directed to promoting dendritic cells (DCs), and optionally M1-type (macrophage M1 polarization), immune response by administering a compound that modulates macrophage polarization. The invention is directed to the use of an antibody able to bind to CSF-1R for modulating macrophage polarization. The invention is also directed to methods for evaluating the dose efficacy of an antibody able to bind to CSF-1R in a patient by assessing the in vivo or in vitro polarization of macrophages. The invention is further directed to post-treatment companion test and assays to assess the effect of an antibody able to bind to CSF-1R on a subject being treated. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10077314-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10336830-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9192667-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017220988-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017220989-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017220990-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11498968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10884000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512133-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10287358-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542335-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046761-B2 |
| priorityDate |
2012-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |