http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014055754-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94b51d317764e2f4f1bbcb355b274c8b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2013-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7c1e441c5978d36ce82bc62ec38a72 |
| publicationDate | 2014-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2014055754-A1 |
| titleOfInvention | Conformationally-constrained kinked endosomal-disrupting peptides |
| abstract | A conformationally-constrained kinked peptide includes: a conformationally- constraining portion and a kinked portion linked to the conformationally-constraining portion that conformationally constrains the kinked portion, the kinked portion comprising an endosomal-disrupting peptide. The peptide can include a peptide sequence of one of SEQ ID NOs: 1, 5-38, or 40-69. The conformationally-constrained kinked portion can be a majority portion or minority of the peptide. The peptide can include one of Formulae 1-lC, wherein: CC-Peptide includes a peptide that conformationally constrains the ED-KP; Peptide independently includes natural, unnatural, essential or non-essential aromatic, aliphatic, or other amino acids having L or D configuration; ED- KP includes an endosomal-disrupting kinked peptide; Xaa, Xaa 1 , and Xaa 2 are independently one or more natural or non-natural amino acids, essential amino acids, or non-essential amino acids, or derivatives of amino acids having L or D configuration; LI and L2 are independently linkers; and nl, n2, n3, and n4 are independently 0-50. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9636419-B2 |
| priorityDate | 2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.