http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014051359-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e06bbf2a93ce8414011cb5ba011faf8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-62 |
| filingDate | 2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d6ea9469e0722cfaa0f7e41c727f68f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82ceb35bbe464335de559dace223c728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec0beda0e29cd979ad2806f4c4602846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73356659aeb0b63b974200f8e9daad91 |
| publicationDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2014051359-A1 |
| titleOfInvention | Pharmaceutical composition comprising neferine as active ingredient for preventing or treating hepatoma |
| abstract | The present invention relates to a novel use of neferine for treating hepatoma, and more particularly, to a pharmaceutical composition and to a health functional food comprising neferine as an active ingredient for preventing or treating hepatoma. The neferine of the present invention can have an anticancer effect through the activities of stopping a cell cycle, inducing apoptosis and autophagy, and inhibiting angiogenesis and cell migration of hepatocarcinoma cells. In particular, since neferine has cytotoxicity specificity for hepatocarcinoma cells caused by viral infection even among hepatocarcinoma cells, the present invention has an effect optimized for treating hepatocarcinoma cells caused by viral infection. Thus, the neferine of the present invention can be used as a health functional food, as well as a medicine such as a pharmacological composition used as a material which can prevent or treat hepatoma. Therefore, it is expected that the value of the present invention is very high when the present invention is applied to the food industry and the pharmaceutical industry. Furthermore, since the neferine of the present invention does not show cytotoxicity for cells other than certain hepatocarcinoma cells, the composition of the present invention, which comprises neferine as an active ingredient, is beneficial in consideration of the safety of long-term use. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109069513-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017142283-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109069513-A |
| priorityDate | 2012-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 493.