| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a9df6734836f928dbfa95a3bb31459c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7069 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
| filingDate |
2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c62b7f9a9498d44a9b675d082b9319
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff39e14947bc6eb71ae27cad6aea5926
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fda3889b428b0e14c81715662a9938c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac53bf806a07d1a58817fe7f50c5f846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dffe2fb3f4500f12ae1ba9eec441deb9 |
| publicationDate |
2014-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014047191-A1 |
| titleOfInvention |
Transdermal drug delivery device |
| abstract |
A transdermal drug delivery device is disclosed for administering an oxidizably and/or hydrolyzably degradable drug, e.g., cholinesterase inhibitors such as rivastigmine. The device comprises a) a substantially impermeable backing layer; b) an adhesive layer substantially free of antioxidant and containing a therapeutically effective amount of the degradable drug, which adhesive drug-containing layer is capable of adhering directly to a subject's skin or to another adhesive layer which is capable of adhering to a subject's skin; and c) a substantially impermeable protective release liner layer which releasably contacts the adhesive drug-containing layer or another adhesive layer. The delivery device is sealed in a degradation protective packaging system, such as a substantially oxygen impermeable heat sealable plastic pouch that contains a substantially inert gas and/or a degradation protectant material for the drug, such as an antioxidant, which can be inserted separately to the pouch. A method of making the device is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015156990-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016121805-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021005118-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10357463-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H10228623-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016121805-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9949935-B2 |
| priorityDate |
2012-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |